Question 721207
What is the most simple method to solve 2^100 = ? (2 exponential 100)?
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"most simple" or simplest can be a matter of opinion.
I would use a calculator.
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You can use logarithms, that was how it was done before calculators.
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PS  It's not solved, there's no variable, no x, y, etc.
It's just evaluated or calculated.