SOLUTION: In a clinical trial 250 patients are randomly assigned to receive either a proposed stroke prevention medication ( ) or a placebo ( ) and are followed over the course of a 5-years
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Question 483269: In a clinical trial 250 patients are randomly assigned to receive either a proposed stroke prevention medication ( ) or a placebo ( ) and are followed over the course of a 5-years study period. These results are given in the following table:
Treatment Group Event
Stroke No Stroke Total
12 108 120
28 102 130
Total 40 210 250
a. Estimate the risk of stroke comparing those on the medication to those on placebo and interpret the result.
b. Interpret your result in part a.
You can put this solution on YOUR website! In a clinical trial 250 patients are randomly assigned to receive either a proposed stroke prevention medication ( ) or a placebo ( ) and are followed over the course of a 5-years study period. These results are given in the following table:
Treatment Group Event
Stroke No Stroke Total
::::::12 108 120
::::::28 102 130
Total 40 210 250
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I'll assume the "12" refers to the treatment group and
the 28 is the not-treatment group.
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So p-hat = 12/120 = 0.10 for the treatment group
and p-hat = 28/130 = 0.22 for the non-treatment group
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Ho: p1-p2 = 0
H1: p1-p2 < 0
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test stat: (0.10-0.22)/sqrt[(0.1*0.9/120)+(0.22*0.78/130)] = -2.6375
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p-value = P(z < -2.6375) = 0.0042
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Conclusion: Since the p-value is less than 1%, reject
Ho at the 1% significance level.
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a. Estimate the risk of stroke comparing those on the medication to those on placebo and interpret the result.
b. Interpret your result in part a.
The non-treatment group is twice as liable have a stroke.
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Cheers,
Stan H.
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