First off, I think it rather arrogant and rude of you to simply dump a problem on this site without any explanation of the difficulty you are having. It is almost as if you are saying "Here you go, Chump, do my homework for me." After all, we are taking the time to help you, so it is a bit much that we should also have to guess what you want.
Be that as it may, it seems as if you want to evaluate the given expression with the given values for the variables. You can do this one of two ways.
One way would be to substitute the values for the variables and then just do the arithmetic:
On the other hand you could recognize that the given expression is the factorization of the sum of two cubes:
