The edge of the cube is 36; the volume of the cube is
Since the cylinder just fits inside the cube, its height is 36 and its radius is 18; its volume is
The volume of empty space is the difference between the two volumes; the percentage of empty space is the ratio of the volume of empty space to the volume of the cube.
You can do the calculations....
Note that the heights of the cube and cylinder are the same; so the ratio of volumes of the two solids is the same as the ratio of the cross sections of the two solids, which is