Presumably that is the expression you need to evaluate. It doesn't take a lot of effort to look at what you are posting before you post it, to see it you are posting it correctly....
1-2+3-4+5-6+...+99-100
Group the terms in pairs:
(1-2)+(3-4)+(5-6)+...+(99-100)
(-1)+(-1)+(-1)+...+(-1)
That's 50 pairs, each with a sum of -1, so the sum of all the numbers is 50(-1) = -50.