The numbers, x and x+16 are the side lengths of a rectangle. This rectangle contains a square of area x^2 and a smaller rectangle of side lengths x and 16. DRAW THE DESCRIPTION!
Cut the x by 16 rectangle in half along the x direction so that you have a rectangle x by 8; and rotate this piece a quarter turn, and put it in contact onto a neighboring x length of the x by x square.
You should find that you now have almost a square shape but with a small square piece missing. WHAT is the area of this small missing piece?
You should find that the missing piece has an area of square units. If you now COMPLETE the SQUARE, you will have a factorable trinomial expression.