There are 26 letters in the alphabet.
There are 26 possibilities for the first letter.
Once that letter is gone, because each letter is different, there are 25 possibilities for the second letter.
3rd letter - 24 possibilities.
4th letter - 23 possibilities.
5th letter - 22 possibilities.
The total number of possibilities is all those multiplied:
26*25*24*23*22=7893600
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