document.write( "<A HREF=/cgi-bin/jump-to-question.mpl?question=263850>Question 263850</A>: <I><SPAN STYLE=\"word-break: break-all;\"> Does Iovastatin (a cholesterol-lowering drug) reduce the risk of heart attack? In a Texas study, researchers gave lovastatin to 2,325 people and an inactive substitute to 2,081 people (average age 58). After 5 years, 57 of the lovastatin group had suffered a heart attack, compared with 97 for the inactive pill. a)State the appropiate hypothesis. b)Obtain a test statistic and p-value, Interpret the results at &#945; = .01. c) Is normality assured? d)Is the difference large enough to be important? e)What else would medical researchers need to know before prescribing this drug widely? (Data are from Science News 153 [May 30, 1998], p, 343. </SPAN>\n" );
document.write( "</I><HR><TABLE width=100%><TR><TD><B><A HREF=http://www.algebra.com/>Algebra.Com's</A> Answer #194452 by </B><A HREF=/tutors/aboutme.mpl?userid=stanbon><B>stanbon(75887)</B></A><img src=\"/images/stars/stars-13.gif\" alt=\"\" >&nbsp;<A HREF=/tutors/aboutme.mpl?userid=stanbon><IMG SRC=http://www.algebra.com/images/aboutme-small.gif BORDER=0 alt=\"About Me\" VALIGN=MIDDLE></A>&nbsp;<IMG SRC=http://www.algebra.com/images/nopicture.jpg><BR>You can <A HREF=\"/cgi-bin/embed-solution.mpl?show=1&solution=194452\">put this solution on YOUR website!</A><BR><SPAN STYLE=\"word-break: break-all;\"> Does lovastatin (a cholesterol-lowering drug) reduce the risk of heart attack? In a Texas study, researchers gave lovastatin to 2,325 people and an inactive substitute to 2,081 people (average age 58). After 5 years, 57 of the lovastatin group had suffered a heart attack, compared with 97 for the inactive pill. <BR>\n" );
document.write( "(a) State the appropriate hypotheses.<BR>\n" );
document.write( "Ho: p(lov)-p(no lov) = 0<BR>\n" );
document.write( "Ha: p(lov)-p(no lov) < 0<BR>\n" );
document.write( "--------------------------------- <BR>\n" );
document.write( "(b) Obtain a test statistic and p-value. Interpret the results at &#945; = .01.<BR>\n" );
document.write( "Using a 2-Prop Z Test on a TI calculator:<BR>\n" );
document.write( "T.S. z((57/2325)-(97/2081)) = -3.9868<BR>\n" );
document.write( "p-value: 0.0000335<BR>\n" );
document.write( "Interp: Less than 0.003% of test results would have provided stronger <BR>\n" );
document.write( "evidence for failing to Reject Ho.<BR>\n" );
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document.write( "(c) Is normality assured?<BR>\n" );
document.write( "Check your conditions <BR>\n" );
document.write( "(d) Is the difference large enough to be important?<BR>\n" );
document.write( "Yes <BR>\n" );
document.write( "(e) What else would medical researchers need to know before Is the difference large enough to be important?<BR>\n" );
document.write( "I'll leave that to you.<BR>\n" );
document.write( "Cheers,<BR>\n" );
document.write( "Stan H.<BR>\n" );
document.write( " </SPAN>\n" );
document.write( "</TD></TR></TABLE>\n" );