We'll start out allowing 0 to be a first digit then we'll 
count those and subtract.

There are 5 positions for the 5 digits.

Choose the position for the 2 in 5 ways.
Choose the position for the 5 in 4 ways.
There are three vacant positions remaining.
Choose a digit to go in the leftmost vacant position 6 ways.
Choose a digit to go in the middle vacant position 5 ways.
Choose a digit to go in the rightmost vacant position 4 ways.

That's (5)(4)(6)(5)(4) = 2400

We must now count the undesired ones, i.e., that begin with 0. 

We can consider these to be 4-digit numbers with digits from
{1, 2, 3, 4, 5, 6, 7} that must include the digits 2 and 5.

There are 4 positions for the 4 digits.

Choose the position for the 2 in 4 ways.
Choose the position for the 5 in 3 ways.
There are two vacant positions remaining.
Choose a digit to go in the leftmost vacant position 5 ways.
Choose a digit to go in the rightmost vacant position 4 ways.

That's (4)(3)(5)(4) = 240

Subtracting, 2400-240 = 2160  <--ANSWER

Edwin