You can
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is a circle with center at (h,k) and radius r.
In your example, h = 2 and k = -3, so the center is at (2,-3).
The first quadrant is where x and y are both positive, and they are numbered counter-clockwise, so
Q1, x > 0, y > 0
Q2, x < 0, y > 0
Q3, x < 0, y < 0
Q4, x > 0, y < 0.
Your center is in Q4.