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or

Start with the given roots.

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Get the real numbers to the left side.

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Square both sides.

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Square "i" to get -1. Square "-i" to get -1.
Since these equations are identical, this means that we can use one equation

FOIL the left side

Add 1 to both sides.

Combine like terms.
So the quadratic equation that has the roots 4+i and 4-i is