# SOLUTION: A clinical trial is planned to compare an experimental medication designed to lower blood pressure to a placebo. Before starting the trial, a pilot study is conducted involving 10

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 Question 521459: A clinical trial is planned to compare an experimental medication designed to lower blood pressure to a placebo. Before starting the trial, a pilot study is conducted involving 10 participants. The objective of the study is to asses how systolic blood pressure changes untreated over time. Systolic blood pressure are measured at baseline and again 4 weeks later. Compute a 95% confidence interval for the mean difference in blood pressure over 4 weeks. Baseline 120 145 130 160 152 143 126 121 115 135 4 weeks 122 142 135 158 155 140 130 120 124 130Answer by stanbon(57377)   (Show Source): You can put this solution on YOUR website!A clinical trial is planned to compare an experimental medication designed to lower blood pressure to a placebo. Before starting the trial, a pilot study is conducted involving 10 participants. The objective of the study is to asses how systolic blood pressure changes untreated over time. Systolic blood pressure are measured at baseline and again 4 weeks later. Compute a 95% confidence interval for the mean difference in blood pressure over 4 weeks. Baseline 120 145 130 160 152 143 126 121 115 135 4 weeks 122 142 135 158 155 140 130 120 124 130 --- Baseline mean: 134.7 4 weeks mean: 135.6 Sample mean difference: 134.7-135.6 = -0.9 --- ME = 6.1357 --- 95% CI: (-7.036,5.2357) =============== Cheers, Stan H. ===============