Question 220477: Does lovastatin (a cholesterol lowering drug) reduce the risk of heart attack? In Texas study, researchers gave lovastatin to 2, 235 people and an inactive substitiue to 2,081 people (average age 58). After 5 years, 57 of the lovastatin group had suffered a heart attack, compared with 97 for the inactive pill. (a.) State the appropriate hypotheses. (b) Obatain a test stateistic and p-value. Interpret the results at a=.01. (c) Is normality assured? (d) Is the difference large enough to be immportant? (e) What else would medical researchers need to kow before prescribing this drug widely?
Answer by stanbon(75887)   (Show Source):
You can put this solution on YOUR website! Does lovastatin (a cholesterol lowering drug) reduce the risk of heart attack? In Texas study, researchers gave lovastatin to 2, 235 people and an inactive substitiue to 2,081 people (average age 58). After 5 years, 57 of the lovastatin group had suffered a heart attack, compared with 97 for the inactive pill.
(a.) State the appropriate hypotheses.
Ho: p(lov)-p(pla) = 0
H1: p(lov)-p(pla) < 0
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(b) Obtain a test statistic and p-value. Interpret the results at a=.01.
I ran a 2-Prop Ztest and got the following:
test stat: z = -3.7366 ; p-value is 0.00009364..
Conclusion: Since p-value is less than 1%, Reject Ho. The lovastatin
reduced the proportion of deaths.
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(c) Is normality assured?
I'll leave that to you.
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(d) Is the difference large enough to be immportant?
Yes, the small p-value shows the strength of the results.
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(e) What else would medical researchers need to know before prescribing this drug widely?
I'll leave that to you.
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Cheers,
Stan H.
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