In 12*11*10*9*8 = 95040 ways. Anyone of 12 amino acid in the 1-st position; Anyone of 11 remaining amino acid in the 2-nd position; Anyone of 10 remaining amino acid in the 3-rd position; Anyone of 9 remaining amino acid in the 4-th position; Anyone of 8 remaining amino acid in the 5-nd position. In all, you get this quantity,= 12*11*10*9*8 = 95040 ways.