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In Math, there is well known Arithmetic Mean - Geometric Mean inequality, which for 3 variables has the form
for any positive real numbers a, b and c >= ,
and inequality becomes an EQUALITY at a = b = c, ONLY.
Apply it to a = x, b = 2y, c = 4z. You will get
>= = = = = 4.
Thus x + 2y + 4z >= 3*4 = 12.
Again, x + 2y + 4z >= 12 for all positive real x, y and z, for which xyz = 8.
Since the equality is ACHIEVED at x = 2y = 4z, the minimum of x + 2y + 4z is 12. ANSWER
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On Arithmetic Mean - Geometric Mean inequality see this Wikipedia article
https://en.wikipedia.org/wiki/Inequality_of_arithmetic_and_geometric_means